Effects of consuming the Neurovegetative Regulating Infusion in an elderly female patient with comorbidities: a clinical case report

Authors

Keywords:

: phytotherapy, Matricaria chamomilla, Tilia spp., tinnitus, elderly, anxiety

Abstract

Acute emotional distress in elderly patients with multiple comorbidities represents a clinical challenge in primary and home care settings. Phytotherapy, through the use of infusions with anxiolytic, sedative, and antispasmodic properties, constitutes a low-cost alternative with broad cultural availability. However, evidence regarding its safety and efficacy in vulnerable populations with a history of tinnitus and arterial hypotension is limited. We report the case of a 76-year-old female with a history of arterial hypotension, tinnitus, environmental allergies, asthma, intercostal neuralgia, and rheumatoid arthritis, who presented with an episode of acute emotional imbalance characterized by crying, facial flushing, distress, and a state of generalized malaise. An infusion composed of chamomile (Matricaria chamomilla L.), linden (Tilia spp.), and dried orange peel (Citrus sinensis), sweetened with honey, was administered at a warm temperature. Ten minutes after ingestion, progressive relaxation, disappearance of facial flushing, and remission of the anxiety symptoms reported by the patient were observed. Subsequently, a transient episode of headache and exacerbation of tinnitus was documented, with blood pressure normalizing to the patient's baseline values in approximately 8 hours. The infusion used produced a clinically observable calming effect in the patient; however, a possible association between chamomile consumption and the transient exacerbation of tinnitus was identified, as well as a transient increase in blood pressure. We highlight the need to measure blood pressure before administering phytotherapy and to consider individual interactions with the medicinal plants used.

 

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Author Biographies

  • Lisandra Duany-Osoria, Instituto MIELSY

    Licenciada en Nutrición. Máster propio en Obstetricia para Matronas. Instituto MIELSY. Guatemala. 

  • Juan Carlos Méndez-Achon, Sucursal Servicios Médicos Ciego de Ávila

    Doctor en Medicina, especialista de I grado en Medicina General Integral. Diplomado en Epidemiologia. Profesor instructor. Sucursal Servicios Médicos Ciego de Ávila. Cuba

References

1. World Health Organization. Ageing and health [Internet]. Geneva: WHO; 2022 [cited 2025 Oct 1]. Available from: https://www.who.int/news-room/fact-sheets/detail/ageing-and-health

2. Marengoni A, Angleman S, Melis R, Mangialasche F, Karp A, Garmen A, et al. Aging with multimorbidity: a systematic review of the literature. Ageing Res Rev. 2011;10(4):430-9. doi: 10.1016/j.arr.2011.03.003

3. Roberts NP, Kitchiner NJ, Kenardy J, Robertson L, Lewis C, Bisson JI. Early psychological intervention following recent trauma: a systematic review and meta-analysis. Eur J Psychotraumatol. 2019;10(1):1695486. doi: 10.1080/20008198.2019.1695486

4. Bhatt JM, Bhattacharyya N, Lin HW. Relationships between tinnitus and the prevalence of anxiety and depression. Laryngoscope. 2017;127(2):466-9. doi: 10.1002/lary.26107

5. Wachtel-Galor S, Benzie IFF. Herbal medicine: an introduction to its history, usage, regulation, current trends, and research needs. In: Benzie IFF, Wachtel-Galor S, editors. Herbal Medicine: Biomolecular and Clinical Aspects. 2nd ed. Boca Raton: CRC Press/Taylor & Francis; 2011.

6. Hieu TH, Dibas A, Surber C, Baser KHC. Therapeutic potential of Matricaria chamomilla: a review. J Complement Integr Med. 2022;19(3):497-510. doi: 10.1515/jcim-2021-0191

7. Gutiérrez SLG, Chilpa RR, Jaime HB. Medicinal plants for the treatment of “nervios”, anxiety, and depression in Mexican Traditional Medicine. Rev Bras Farmacogn. 1 de septiembre de 2014;24(5):591-608. doi:10.1016/j.bjp.2014.10.007

8. Mannucci C, Calapai F, Cardia L, Inferrera G, D’Arena G, Di Pietro M, et al. Clinical Pharmacology of Citrus aurantium and Citrus sinensis for the Treatment of Anxiety. Evid-Based Complement Altern Med ECAM. 2 de diciembre de 2018;2018:3624094. doi:10.1155/2018/3624094 PubMed PMID: 30622597; PubMed Central PMCID: PMC6304613.

9. Posadzki P, Watson L, Ernst E. Adverse effects of herbal medicines: an overview of systematic reviews. Clin Med (Lond). 2013;13(1):7-12. doi: 10.7861/clinmedicine.13-1-7

10. Ulrich-Lai YM, Herman JP. Neural regulation of endocrine and autonomic stress responses. Nat Rev Neurosci. 2009;10(6):397-409. doi: 10.1038/nrn2647

11. Canto YE, Gervasi GD, Alvirio LM, Mena RP. Effects of Plant Extract and Dietary Supplements on Tinnitus Perception in Adults: A Systematic Review and Meta-Analysis. Rev Esp Nutr Humana Dietética. 14 de marzo de 2025;29(1). doi:10.14306/renhyd.29.1.2308

12. Hieu TH, Dibas A, Surber C, Baser KHC. Chamomile: A herbal medicine of the past with bright future. Mol Med Rep. 2021;24(5):1-7. doi: 10.3892/mmr.2021.12399

13. Riley DS, Barber MS, Kienle GS, Aronson JK, von Schoen-Angerer T, Tugwell P, et al. CARE guidelines for case reports: explanation and elaboration document. J Clin Epidemiol. 2017;89:218-35. doi: 10.1016/j.jclinepi.2017.04.026

14. Canto YE, Gervasi GD, Alvirio LM, Mena RP. Effects of Plant Extract and Dietary Supplements on Tinnitus Perception in Adults: A Systematic Review and Meta-Analysis. Rev Esp Nutr Humana Dietética. 14 de marzo de 2025;29(1). doi:10.14306/renhyd.29.1.2308

15. Srivastava JK, Shankar E, Gupta S. Chamomile: A herbal medicine of the past with bright future. Mol Med Rep. 2010;3(6):895-901. doi: 10.3892/mmr.2010.377

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Published

2026-06-15

How to Cite

1.
Duany-Osoria L, Méndez-Achon JC. Effects of consuming the Neurovegetative Regulating Infusion in an elderly female patient with comorbidities: a clinical case report. Rev. Conex. Cienc. Neuroarte Bienest [Internet]. 2026 Jun. 15 [cited 2026 Jun. 20];2(1-3):027. Available from: https://editorial.mielsy.org/index.php/RCCNB/article/view/e0027